{"id":30120,"date":"2024-12-30T21:58:52","date_gmt":"2024-12-30T20:58:52","guid":{"rendered":"https:\/\/www.mylav.net\/?p=30120"},"modified":"2024-12-30T21:58:52","modified_gmt":"2024-12-30T20:58:52","slug":"novi-nalaz-kompletne-krvne-slike-hemogram-mylav-upute-za-koristenje","status":"publish","type":"post","link":"https:\/\/www.mylav.net\/hr\/blog-hr\/novi-nalaz-kompletne-krvne-slike-hemogram-mylav-upute-za-koristenje\/","title":{"rendered":"Novi nalaz KOMPLETNE KRVNE SLIKE (hemogram) Mylav: upute za kori\u0161tenje."},"content":{"rendered":"

Nalaz hemograma MyLav dolazi u novom formatu: ova odluka proizlazi iz potrebe prilagodbe najmodernijim tehnologijama i udovoljavanja zahtjevima klini\u010dara, pojednostavljuju\u0107i informacije sadr\u017eane u hemogramu te ih \u010dine\u0107i lak\u0161e dostupnima. Evo \u0161to se konkretno mijenja.
\n<\/span>Osnovna tehnologija prelazi sa starijeg modela ADVIA-Siemens na noviju tehnologiju Sysmex, ure\u0111aj koji kombinira impedancijsku tehnologiju s laserskom tehnologijom.
\n<\/span>Naravno, ve\u0107ina klasi\u010dnih podataka dobivenih u hemogramu ne\u0107e se promijeniti, dok \u0107e biti uvedene odre\u0111ene novosti u nalazu, opisane u nastavku prema tipologiji stanica.<\/span><\/p>\n

\"\"<\/p>\n

Eritrociti<\/strong><\/p>\n

\u0160to se ti\u010de eritrocita, kombinacija mjerenja impedancije i opti\u010dkih o\u010ditanja omogu\u0107uje zadr\u017eavanje svih informacija prisutnih u prethodnom nalazu, iako \u0107e u nekim slu\u010dajevima oznaka u nalazu biti druga\u010dija: broj eritrocita (RBC), hematokrit (HCT), ukupna koncentracija hemoglobina (HGB) i \u0161irina raspodjele volumena eritrocita (RDW) ostaju nepromijenjeni.<\/span><\/p>\n

Eritrocitni HGB (cellular HGB u prethodnom nalazu) sada se definira kao HGB-O prema novom ure\u0111aju. Klasi\u010dni eritrocitni indeksi ostaju nepromijenjeni: prisutni su prosje\u010dni obujam eritrocita (MCV), prosje\u010dna masa hemoglobina po eritrocitu (MCH) i prosje\u010dna koncentracija hemoglobina u jednoj litri obujma eritrocita (MCHC).<\/span><\/p>\n

Prosje\u010dan sadr\u017eaj hemoglobina dobiven iz unutar eritrocitnog HGB-a (CH u prethodnom nalazu) sada se ozna\u010dava kao RBC-He. Prosje\u010dna koncentracija hemoglobina\u00a0 izra\u010dunata iz eritrocitnog HGB-a (ranije nazvana MCHC) sada nosi naziv MCHC-O.<\/span><\/p>\n

Sysmex sustav omogu\u0107uje precizno kvantificiranje eritrocita s jezgrama (nRBC): ure\u0111aj stoga daje broj eritrocita s jezgrama na svakih 100 leukocita (nRBC\/100 WBC) kao i apsolutnu vrijednost eritrocita s jezgrama (nRBC x 10\u00b3\/\u00b5L).<\/span><\/p>\n

Retikulociti<\/strong><\/p>\n

Profil retikulocita pojednostavljen je kako bi prikazivao samo klini\u010dki najkorisnije parametre koji su ve\u0107 bili prisutni u prethodnom nalazu, posebno: postotak i apsolutni broj retikulocita (RET), postotke retikulocita s niskom (L-RET), srednjom (M-RET) i visokom (H-RET) fluorescencijom, \u0161to odgovara gotovo zrelim, umjereno nezrelim i vrlo nezrelim retikulocitima; ove posljednje dvije kategorije zatim su objedinjene u ukupnu vrijednost nezrelih retikulocita (IRF), kao i u prethodnom nalazu.<\/span><\/p>\n

Sadr\u017eaj hemoglobina u retikulocitima, prethodno izra\u017een kao CHr, sada se izra\u017eava kao Ret-He. Kao i prije, izra\u010dunava se i korigirani postotak retikulocita na temelju hematokrita te indeks proizvodnje retikulocita (RPI).<\/span><\/p>\n

Leukociti<\/strong><\/p>\n

Podaci o leukogramu ostaju nepromijenjeni u odnosu na prethodni nalaz, uklju\u010duju\u0107i ukupan broj leukocita (WBC) te broj i postotak razli\u010ditih populacija leukocita (neutrofili, uklju\u010duju\u0107i trakaste ako su prisutni, eozinofili, bazofili, limfociti i monociti).<\/span><\/p>\n

Va\u017eno je naglasiti da ukupan broj leukocita odgovara onome \u0161to je u prethodnom nalazu bilo ozna\u010deno kao WBC kor., budu\u0107i da je u prethodnom hemogramu bilo potrebno korigirati instrumentalni broj leukocita za broj eritrocita sa jezgrom (nRBC) brojenih pod mikroskopom. U trenutnom nalazu eritrociti sa jezgrom se broje odvojeno pomo\u0107u Sysmex sustava, kako je ve\u0107 prethodno navedeno<\/span><\/p>\n

Trombociti<\/strong><\/p>\n

Za procjenu trombocita u nalaz su uklju\u010deni samo klini\u010dki najva\u017eniji podaci koji su ve\u0107 bili prisutni u prethodnom hemogramu, poput broja trombocita (PLT), srednjeg volumena trombocita (MPV), trombokrita (PCT), i udjela velikih trombocita (P-LCR – large platelets).<\/span><\/p>\n

Uz ove indekse, kod \u017eivotinja s trombocitopenijom, dodana je i postotna vrijednost nezrelih trombocita (IPF ili immature platelet fraction), koja raste kod trombocitopenija uzrokovanih gubitkom\/perifernom destrukcijom, ali ne i kod poreme\u0107aja ko\u0161tane sr\u017ei koji smanjuju proizvodnju trombocita.<\/span><\/p>\n

Na kraju, u nalazu ostaju sve relevantne morfolo\u0161ke anomalije krvnih stani\u010dnih populacija, koje se provjeravaju mikroskopski od strane stru\u010dnjaka, kao i druge patolo\u0161ke anomalije uo\u010dene tijekom pretrage krvnog razmaza (npr. uzro\u010dnici bolesti)<\/span><\/p>\n

 <\/p>\n

Bibliografija<\/strong>:<\/span><\/p>\n

1: Guerlin M, Granat F, Grebert M, Braun JP, Geffr\u00e9 A, Bourg\u00e8s-Abella N, Trumel C. Validation of the Sysmex XN-V hematology analyzer for feline specimens. Vet Clin Pathol. 2024 Sep;53(3):294-308.<\/span><\/p>\n

2: Perez-Ecija A, Martinez C, Fernandez-Casta\u00f1er J, Mendoza FJ. Utility of immature platelet fraction in the Sysmex XN-1000V for the differential diagnosis of central and peripheral thrombocytopenia in dogs and cats. J Vet Intern Med. 2024 May-Jun;38(3):1512-1519.<\/span><\/p>\n

3: Ginders J, Stirn M, Novacco M, Hofmann-Lehmann R, Riond B. Validation of the Sysmex XN-V Automated Nucleated Red Blood Cell Enumeration for Canine and Feline EDTA-Anticoagulated Blood. Animals (Basel). 2024 Jan 30;14(3):455.<\/span><\/p>\n

4: Perez-Ecija A, Martinez C, Fernandez-Casta\u00f1er J, Mendoza FJ. The Immature Reticulocyte Fraction (IRF) in the Sysmex XN-1000V Analyzer Can Differentiate between Causes of Regenerative and Non-Regenerative Anemia in Dogs and Cats. Animals (Basel). 2024 Jan 22;14(2):349.<\/span><\/p>\n

5: Jornet-Rius O, Mesalles-Naranjo M, Pastor J. Performance of the Sysmex XN-V hematology analyzer in determining the immature platelet fraction in dogs: A preliminary study and reference values. Vet Clin Pathol. 2023 Sep;52(3):433-442.<\/span><\/p>\n

6: Grebert M, Granat F, Braun JP, Leroy Q, Bourg\u00e8s-Abella N, Trumel C. Validation of the Sysmex XN-V hematology analyzer for canine specimens. Vet Clin Pathol. 2021 Jun;50(2):184-197.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Nalaz hemograma MyLav dolazi u novom formatu: ova odluka proizlazi iz potrebe prilagodbe najmodernijim tehnologijama […]<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[805],"tags":[],"class_list":["post-30120","post","type-post","status-publish","format-standard","hentry","category-blog-hr"],"acf":[],"yoast_head":"\nNovi nalaz KOMPLETNE KRVNE SLIKE (hemogram) Mylav: upute za kori\u0161tenje. - MyLav<\/title>\n<meta name=\"description\" content=\"Nalaz hemograma MyLav dolazi u novom formatu: ova odluka proizlazi iz potrebe prilagodbe najmodernijim tehnologijama i udovoljavanja zahtjevima klini\u010dara, pojednostavljuju\u0107i informacije sadr\u017eane u hemogramu te ih \u010dine\u0107i lak\u0161e dostupnima. 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